Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig's Disease, is a rare neurological disease that affects motor neurons — those nerve cells in the brain and spinal cord that control voluntary muscle movement. As motor neurons degenerate and die, they stop sending messages to the muscles, which causes the muscles to weaken, start to twitch (fasciculations), and waste away (atrophy). Eventually, the brain loses its ability to initiate and control voluntary movements. In this report, we will explore the available treatment options and the ALS landscape.