AdisInsight informing on drug development in vaccines

Over the last 50 years, billions of vaccines have been administered to prevent disease. Globally, immunizations prevent 2-3 million deaths annually from diseases like tetanus, pertussis, influenza, and measles. In 2019, the WHO reported that 86% of infants worldwide received three doses of diphtheria, tetanus, and pertussis vaccinations. 

Since the onset of the COVID-19 pandemic, vaccination development has become a global point of focus. And while the development of the COVID-19 vaccinations occurred at a faster pace than traditionally seen, this development is still held to the same standards as other vaccinations. AdisInsight can help you keep up with the rapid pace of vaccine development within infectious disease. It is an integrated database of profiles authored by Springer Nature editors sourced from publicly available information from journals, conferences, trial registries, media releases, company websites, and government filings about pharmaceutical development programs, clinical trial studies, and published individual case safety reports. Information in AdisInsight is updated daily to keep you informed of the latest information impacting your research. Start searching on AdisInsight.


Global Drug Pipeline

According to AdisInsight, the global drug pipeline for the drug class Vaccines currently contain 3,819 unique programs that are either marketed, in regulatory approval, in clinical development, in preclinical development, or have been discontinued.

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Global Clinical Trial Landscape

AdisInsight shows 8,695 clinical studies investigating the drug class Vaccines being conducted in 174 countries. Some of these studies will be active in either the planning, recruitment, or administration stage while other will be inactive, completed, or discontinued.  


New Content Item (1)The clinical trial map shown here aggregates information across all trials researching vaccines to show where active clinical studies are taking place at a regional level.


Organizations Active in Vaccines

According to AdisInsight there are 2,658 organizations involved in researching drug development programs for vaccines.  1,796 of these organizations have vaccines in active development. The table below shows the top 15 organizations ranked according by the number of drug programs in development for vaccines. 

Many of these organizations use AdisInsight to inform their strategic decisions as they work to advance vaccine development. Whether they are identifying unmet clinical needs, monitoring the therapy area landscape, researching innovative disease targets, or planning clinical trial programs, AdisInsight is making drug development more efficient. 

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Biomarkers for Vaccines

Biomarker selection is becoming an essential part of clinical development. Successful use of biomarkers can accelerate the pace of development by predicting drug efficacy more quickly, identifying optimal patient populations, and early detection of safety signals.

AdisInsight catalogs 129 biomarkers associated with the drug class of vaccines. 57 of biomarkers are being used as outcome measures, 31 are being used for patient inclusion, 12 for patient exclusion, and 7 are being used to detect safety issues. The top 15 biomarkers being used in vaccine research are shown below.
 

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