Nobel Prize at Springer Nature

2024 Nobel Prize in Physiology or Medicine

Nobel Prize 2018

On October 7, the Nobel Prize in Physiology or Medicine 2024 was jointly awarded to Victor Ambros and Gary Ruvkun "for the discovery of microRNA and its role in post-transcriptional gene regulation."*

This year’s Nobel Laureates didn’t achieve their breakthroughs overnight. Below you can read, share, and download a selection of their research that’s published across Springer Nature’s journals and books. Read the story of this year’s Laureates in Physiology or Medicine.

*The Nobel Prize in Physiology or Medicine 2024 - NobelPrize.org

Publications by Gary Ruvkun

Articles

MicroRNA-responsive 'sensor' transgenes uncover Hox-like and other developmentally regulated patterns of vertebrate microRNA expression. Published in: Nature Genetics

Graded expression of ceh-14 reporters in the hypodermis is induced by a gonadal signal. Published in: Development Genes and Evolution

The Most Conserved Genome Segments for Life Detection on Earth and Other Planets. Published in: Origins of Life and Evolution of Biospheres

Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA. Published in: Nature

The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans. Published in: Nature

The Caenorhabditis elegans heterochronic gene lin-14 encodes a nuclear protein that forms a temporal developmental switch. Published in: Nature

A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans. Published in: Nature

The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans. Published in: Nature

Food and metabolic signalling defects in a Caenorhabditis elegans serotonin-synthesis mutant. Published in: Nature

more

A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity. Published in: Nature Genetics

Polygenic control of Caenorhabditis elegans fat storage. Published in: Nature Genetics

MXL-3 and HLH-30 transcriptionally link lipolysis and autophagy to nutrient availability. Published in: Nature Cell Biology

Lipid signalling couples translational surveillance to systemic detoxification in Caenorhabditis elegans. Published in: Nature Cell Biology

Book chapters

Signaling Pathways that Regulate C. elegans Life Span. Published in: IGFs:  Local Repair and Survival Factors Throughout Life Span

Regulation of C. Elegans Life Span by Insulin-Like Signaling. Published in: Endocrine Aspects of Successful Aging:  Genes, Hormones and Lifestyles

Generation of Temporal and Cell Lineage Asymmetry During C. elegans Development. Published in: Development:  The Molecular Genetic Approach

Molecular Cloning of Nitrogen Fixation Genes from Rhizobium Meliloti. Published in: Genetic Engineering of Symbiotic Nitrogen Fixation and Conservation of Fixed Nitrogen

L_brandstrip_bmc
L_brandstrip_natureresearch
L_brandstrip_springer