The separation of very polar molecules had its origins many decades ago - despite this, apart from IC, no other techniques have been able to establish themselves in most laboratories. What you can use and how you use the technology is important to know and can be learned!
Course combines theory, practice and expert tips
Course content and process
Contents Polar Chromatography
- Apparatus setup of HPLC and SFC
- Basic terms in IC, HILIC and SFC
- Basic concepts in further polar chromatography techniques
Content HILIC(-MS)
- Separation and detection of very polar molecules with HILIC-MS
- Stationary HILIC phases (for MS coupling)
- Mobile HILIC phases (for MS coupling)
- Other necessary conditions for MS coupling
Contents SFC(-MS)
- Separation and detection of very polar molecules with SFC-MS
- Stationary SFC phases (for MS coupling)
- Mobile SFC phases (for MS coupling)
- Other necessary conditions for MS coupling
- Content Application of polar chromatography
- Examples from the fields of bioanalysis, environmental analysis and food analysis
- Screening approaches for polar molecules
- Examples of course participants (if known in advance)
Contents Chromatographic couplings
- LC-LC-MS systems for the simultaneous detection of molecules of different polarity
- RPLC-HILIC-MS: structure and application
- 2D- LC-MS: structure and application
Your top speaker:
PD Dr. habil. Thomas Letzel, born in 1970, studied chemistry (1992-1998) at the Technical University of Munich and the LMU Munich and received his doctorate in 2001 with an environmental analysis topic at the Technical University of Munich and then completed a two-year postdoctoral stay at the Vrijen Universiteit Amsterdam. In 2009 he habilitated at the Technical University of Munich, where he has been teaching and researching as a private lecturer ever since. Until 2018 he was head of the analytical research group AFG at the TUM, 2014-2017 acting head of the professorship for pharmaceutical analysis at the LMU and has been the founder and managing director of the Analytical Research Institute for Non-Target Screening GmbH (AFIN-TS) since 2018. To date, he has developed many new analytical platforms, workflows and strategies for the detection, identification and determination of functional properties of organic molecules from complex mixtures in the various scientific disciplines. The results are reflected in his more than 75 scientific publications and 4 books to date.
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